CDC123 Antibody

Rabbit mAb

Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	WB, FC, IP
Primary Accession	O75794
Reactivity	Rat, Human, Mouse
Clonality	Monoclonal
Other Names	C10orf7; CDC123; Cell division cycle 123; D123; HT 1080; PZ32;
Isotype	Rabbit IgG
Host	Rabbit
Calculated MW	39135 Da

Additional Information
Dilution	WB 1:500~1:2000 IP 1:50 FC 1:50
Purification	Affinity-chromatography
Immunogen	A synthesized peptide derived from human CDC123
Description	Required for S phase entry of the cell cycle.
Storage Condition and Buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Protein Information
Name	CDC123
Synonyms	C10orf7, D123
Function	ATP-dependent protein-folding chaperone for the eIF2 complex (PubMed:35031321, PubMed:37507029). Binds to the gamma subunit of the eIF2 complex which allows the subunit to assemble with the alpha and beta subunits (By similarity).
Cellular Location	Cytoplasm {ECO:0000250\|UniProtKB:Q62834}.
Tissue Location	Widely expressed. Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocytes with the highest expression in testis.