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>   首页   >   产品   >   重组兔单克隆抗体   >   重组兔单克隆抗体   >   CTP synthase / CTPS Antibody   

CTP synthase / CTPS Antibody

Rabbit mAb

     
  • 0 - CTP synthase / CTPS Antibody AP92913
    Western blot analysis of CTP synthase / CTPS expression in HeLa cell lysate.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, FC
Primary Accession P17812
Reactivity Human, Mouse
Clonality Monoclonal
Other Names CTP synthase 1; CTPS; IMD24;
Isotype Rabbit IgG
Host Rabbit
Calculated MW 66690 Da
Additional Information
Dilution WB 1:500~1:2000 FC 1:50
Purification Affinity-chromatography
Immunogen A synthesized peptide derived from human CTP synthase / CTPS
Description CTP synthase (CTPS) catalyzes the ATP-dependent conversion of UTP to CTP using either L-glutamine or ammonia as the source of nitrogen. The enzyme is important in the biosynthesis nucleic acids. It has a key role in cell growth, development, and tumorigenesis.
Storage Condition and Buffer Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Protein Information
Name CTPS1 (HGNC:2519)
Function This enzyme is involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen. This enzyme and its product, CTP, play a crucial role in the proliferation of activated lymphocytes and therefore in immunity.
Cellular Location Cytoplasm, cytosol. Note=Mainly cytosolic but when active detected in long filamentous structures (PubMed:25223282). Co-localizes with TNK2 in the cytosolic filaments (By similarity). {ECO:0000250|UniProtKB:P70698, ECO:0000269|PubMed:25223282}
Tissue Location Widely expressed..
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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