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>   首页   >   产品   >   重组兔单克隆抗体   >   重组兔单克隆抗体   >   Serine racemase Antibody   

Serine racemase Antibody

Rabbit mAb

     
  • 0 - Serine racemase Antibody AP93077
    Western blot analysis of Serine racemase expression in (1) 293 cell lysate; (2) U-87 MG cell lysate.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q9GZT4
Reactivity Human
Clonality Monoclonal
Other Names D serine ammonia lyase; ILV1; ISO1; L serine ammonia lyase;
Isotype Rabbit IgG
Host Rabbit
Calculated MW 36566 Da
Additional Information
Dilution WB 1:500~1:2000
Purification Affinity-chromatography
Immunogen A synthesized peptide derived from human Serine racemase
Description Catalyzes the synthesis of D-serine from L-serine. D-serine is a key coagonist with glutamate at NMDA receptors. Has dehydratase activity towards both L-serine and D-serine.
Storage Condition and Buffer Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Protein Information
Name SRR
Function Catalyzes the synthesis of D-serine from L-serine (PubMed:20106978, PubMed:23391306, PubMed:29277459). D-serine is a key coagonist with glutamate at NMDA receptors. Has dehydratase activity towards both L-serine and D-serine (By similarity).
Tissue Location Expressed in the cerebellum, hippocampus, dorsolateral prefrontal cortex, and in motor neurons and glial cells of the lumbar spinal cord (at protein level) (PubMed:17880399, PubMed:24138986). Increased in the dorsolateral prefrontal cortex of schizophrenic patients (at protein level) (PubMed:17880399). Brain: expressed at high levels in hippocampus and corpus callosum, intermediate levels in substantia nigra and caudate, and low levels in amygdala, thalamus, and subthalamic nuclei (PubMed:15193426). Expressed in heart, skeletal muscle, kidney, and liver (PubMed:15193426)
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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