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PRCC Rabbit Polyclonal Antibody

PRCC Rabbit Polyclonal Antibody

     
  • 1 - PRCC Rabbit Polyclonal Antibody AP93453
    Western blot analysis of lysates from MCF-7 cells, primary antibody was diluted at 1:1000, 4°over night
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q92733
Reactivity Rat, Human, Mouse
Host Polyclonal, Rabbit,IgG
Clonality Polyclonal
Calculated MW 52418 Da
Additional Information
Gene ID 5546
Other Names Proline-rich protein PRCC, Papillary renal cell carcinoma translocation-associated gene protein, PRCC, TPRC
Dilution WB~~1:1000
Storage Conditions-20℃
Protein Information
Name PRCC
Synonyms TPRC
Function May regulate cell cycle progression through interaction with MAD2L2.
Cellular Location Nucleus.
Tissue Location Ubiquitous in fetal and adult tissues.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

This gene encodes a protein that may play a role in pre-mRNA splicing. Chromosomal translocations (X;1)(p11;q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma. A PRCC-TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation. This fusion protein has also been associated with disruption of the cell cycle.[provided by RefSeq, Aug 2010],

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