PRCC Rabbit Polyclonal Antibody
PRCC Rabbit Polyclonal Antibody
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Application ![]()
| WB |
---|---|
Primary Accession | Q92733 |
Reactivity | Rat, Human, Mouse |
Host | Polyclonal, Rabbit,IgG |
Clonality | Polyclonal |
Calculated MW | 52418 Da |
Gene ID | 5546 |
---|---|
Other Names | Proline-rich protein PRCC, Papillary renal cell carcinoma translocation-associated gene protein, PRCC, TPRC |
Dilution | WB~~1:1000 |
Storage Conditions | -20℃ |
Name | PRCC |
---|---|
Synonyms | TPRC |
Function | May regulate cell cycle progression through interaction with MAD2L2. |
Cellular Location | Nucleus. |
Tissue Location | Ubiquitous in fetal and adult tissues. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This gene encodes a protein that may play a role in pre-mRNA splicing. Chromosomal translocations (X;1)(p11;q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma. A PRCC-TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation. This fusion protein has also been associated with disruption of the cell cycle.[provided by RefSeq, Aug 2010],

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