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VPS45A Rabbit pAb
- 产品详情
- 实验流程
Application 
| IHC-P, IHC-F, IF |
|---|---|
| Primary Accession | Q9NRW7 |
| Other Accession | Q9NRW7 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 65077 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human VPS45A |
| Epitope Specificity | 401-500/570 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Belongs to the STXBP/unc-18/SEC1 family. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec1 domain family, and shows a high degree of sequence similarity to mouse, rat and yeast Vps45. The exact function of this gene is not known, but its high expression in peripheral blood mononuclear cells suggests a role in trafficking proteins, including inflammatory mediators. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2013] |
| Gene ID | 11311 |
|---|---|
| Other Names | VPS45A; H1; H1VPS45; SCN5; VPS45B; VPS54A; VSP45; VSP45A; mVps45; VPS45_HUMAN; VPS45; h-VPS45; hlVps45; VPS45_MOUSE; VPS45_RAT; rVps45; vacuolar protein sorting 45 homolog; vacuolar protein sorting 45A (yeast homolog); vacuolar protein sorting 45A (yeast); vacuolar protein sorting 45 homolog (S. cerevisiae) |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | VPS45 |
|---|---|
| Synonyms | VPS45A, VPS45B |
| Function | May play a role in vesicle-mediated protein trafficking from the Golgi stack through the trans-Golgi network. |
| Cellular Location | Golgi apparatus membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein Note=Associated with Golgi/endosomal vesicles and the trans-Golgi network. |
| Tissue Location | Ubiquitous. Expression was highest in testis, heart and brain, intermediate in kidney, spleen, prostate, ovary, small intestine and thymus and low in lung, skeletal muscle, placenta, colon, pancreas, peripheral blood leukocytes and liver |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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