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>   首页   >   产品   >   一抗   >   其他   >   ECP Recombinant Rabbit mAb   

ECP Recombinant Rabbit mAb

     
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P, IHC-F, IF, E
Primary Accession P12724
Other Accession P12724
Host Rabbit
Clonality Recombinant
Calculated MW 18385 Da
Isotype IgG
Purity affinity purified by Protein A
Buffer 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
SIMILARITY Belongs to the pancreatic ribonuclease family.
Background Descriptions The protein encoded by this gene belongs to the pancreatic ribonuclease family, a subset of the ribonuclease A superfamily. The protein exhibits antimicrobial activity against pathogenic bacteria [provided by RefSeq, Oct 2014],
Additional Information
Gene ID 6037
Other Names ECP; RAF1; RNS3; Rnase3; mR3; EAR; Ear11; R1; R7; ECP_HUMAN; Ribonuclease 3 (RNase 3); 3.1.27.-; ECP3_MOUSE; Ear3; MR-3; ECP_RAT; Eosinophil secondary granule ribonuclease 11 (EAR-11); ribonuclease A family member 3; ribonuclease, RNase A family, 3; eosinophil cationic protein; Ribonuclease 3; RNase 3
Dilution IHC-P=1:50-200,IHC-F=1:50-200,WB=1:500-2000,IF=1:50-200,ELISA=1:5000-10000
StorageStore at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name RNASE3
Synonyms ECP, RNS3
Function Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. Promotes E.coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content.
Cellular Location Secreted. Note=Located in the matrix of eosinophil large specific granule, which are released following activation by an immune stimulus
Research Areas
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