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GPD2 Rabbit pAb

     
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
IHC-P, IHC-F, IF
Primary Accession P43304
Other Accession P43304
Host Rabbit
Clonality Polyclonal
Calculated MW 80853 Da
Physical State Liquid
Immunogen KLH conjugated synthetic peptide derived from human GPD2
Epitope Specificity 165-270/727
Isotype IgG
Purity affinity purified by Protein A
Buffer 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
SIMILARITY Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. Contains 2 EF-hand domains.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Background Descriptions The protein encoded by this gene localizes to the inner mitochondrial membrane and catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate, using FAD as a cofactor. Along with GDP1, the encoded protein constitutes the glycerol phosphate shuttle, which reoxidizes NADH formed during glycolysis. Two transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Jan 2010].
Additional Information
Gene ID 2820
Other Names GDH2; GPDM; mGDH; mGPDH; GPDH; Gdm1; Gpd-m; Gpdh-m; TISP38; mtGPDH; GPDM_HUMAN; GPD2; mitohondrial glycerophosphate dehydrogenase gene (mGDH); mtGPD; 1.1.5.3; GPDM_MOUSE; Protein TISP38; GPDM_RAT; glycerol-3-phosphate dehydrogenase 2; glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
Dilution IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
StorageStore at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name GPD2 (HGNC:4456)
Function Calcium-responsive mitochondrial glycerol-3-phosphate dehydrogenase which seems to be a key component of the pancreatic beta- cell glucose-sensing device.
Cellular Location Mitochondrion.
Research Areas
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