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BCAT1 Rabbit pAb
- 产品详情
- 实验流程
Application 
| WB, IHC-P, IHC-F, IF |
|---|---|
| Primary Accession | P54687 |
| Other Accession | P54687 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 42966 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human BCAT1 |
| Epitope Specificity | 321-386/386 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. |
| SUBUNIT | Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2010]. |
| Gene ID | 586 |
|---|---|
| Other Names | BCATC; BCT1; ECA39; MECA39; PNAS121; PP18; BCAT1_HUMAN; BCAT1; BCAT(c); 2.6.1.42; BCAT1_MOUSE; branched chain amino acid transaminase 1; branched chain aminotransferase 1, cytosolic |
| Dilution | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | BCAT1 |
|---|---|
| Synonyms | BCT1, ECA39 {ECO:0000303|PubMed:8692959} |
| Function | Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. |
| Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:P54690}. |
| Tissue Location | During embryogenesis, expressed in the brain and kidney. Overexpressed in MYC-induced tumors such as Burkitt's lymphoma |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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¥ 1,250.00
Cat# AP99314
