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Anti-CSF2Ra / GM-CSFRa / CD116 Reference Antibody (mavrilimumab)

Recombinant Antibody

Anti-CSF2Ra / GM-CSFRa / CD116 Reference Antibody (mavrilimumab) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 95%.
The purity of Anti-CSF2Ra / GM-CSFRa / CD116 Reference Antibody (mavrilimumab) is 96.17%, determined by SEC-HPLC.
Immobilized human CD116 His at 2 ug/mL can bind Anti-CSF2Ra / GM-CSFRa / CD116 Reference Antibody (mavrilimumab), EC50=0.01299 ug/mL.

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Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	Functional assay, Kinetics (SPR), Kinetics (BLI), FACS, E, FTA
Primary Accession	P15509
Reactivity	Cynomolgus, Human
Clonality	Monoclonal
Isotype	IgG4SP
Calculated MW	46207 Da

Additional Information
Target/Specificity	CSF2Ra / GM-CSFRa / CD116
Endotoxin	< 0.001EU/ µg,determined by LAL method.
Conjugation	Unconjugated
Expression system	CHO
Format	Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column.

For Research Use Only. Not For Use In Diagnostic Procedures.

Patent Notice: The variable region sequence of this antibody is derived from a published third-party patent. This product is manufactured independently as a Research Use Only (RUO) reagent and is not licensed, sponsored, or endorsed by the patent holder. It is intended solely for research purposes. Customers considering any commercial, diagnostic, or therapeutic use should independently evaluate freedom-to-operate with respect to relevant third-party patents.

Protein Information
Name	CSF2RA
Synonyms	CSF2R, CSF2RY
Function	Low affinity receptor for granulocyte-macrophage colony- stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells.
Cellular Location	Cell membrane; Single-pass type I membrane protein [Isoform 4]: Secreted.

Research Areas

Application Protocols

Provided below are standard protocols that you may find useful for product applications.

Western Blot Protocol

Blocking Peptides Protocol

Dot Blot Protocol

Immunohistochemistry Protocol

Immunofluorescence Protocol

Immunoprecipitation Protocol

Flow Cytomety Protocol

Cell Culture Protocol