Anti-TNFRSF9 / 4-1BB / CD137 Reference Antibody (utomilumab)

Recombinant Antibody

Anti-TNFRSF9 / 4-1BB / CD137 Reference Antibody (utomilumab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%
The purity of Anti-TNFRSF9 / 4-1BB / CD137 Reference Antibody (utomilumab)is more than 98.78% ,determined by SEC-HPLC.
Immobilized human TNFRSF9 / 4 1BB / CD137, His Tag at 2 µg/mL can bind Anti-TNFRSF9 / 4-1BB / CD137 Reference Antibody (utomilumab)，EC50=0.006915 µg/mL

Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	FC, Kinetics, Animal Model
Primary Accession	Q07011
Reactivity	Human
Clonality	Monoclonal
Isotype	IgG2SA
Calculated MW	27899 Da

Additional Information
Target/Specificity	TNFRSF9 / 4-1BB / CD137
Endotoxin	< 0.001EU/ µg,determined by LAL method.
Conjugation	Unconjugated
Expression system	CHO Cell
Format	Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column.

Protein Information
Name	TNFRSF9
Synonyms	CD137, ILA
Function	Receptor for TNFSF9/4-1BBL. Conveys a signal that enhances CD8(+) T-cell survival, cytotoxicity, and mitochondrial activity, thereby promoting immunity against viruses and tumors (Probable).
Cellular Location	Cell membrane; Single-pass type I membrane protein
Tissue Location	Expressed on the surface of activated T-cells.

Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

Application Protocols

Provided below are standard protocols that you may find useful for product applications.