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Anti-STAB1 Reference Antibody (bexmarilimab)

Recombinant Antibody

Anti-STAB1 Reference Antibody (bexmarilimab) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 95%.
The purity of Anti-STAB1 Reference Antibody (bexmarilimab) is 100%, determined by SEC-HPLC.
Immobilized human STAB His at 2 ug/mL can bind Anti-STAB1 Reference Antibody (bexmarilimab), EC50=0.06461 ug/mL.
Human STAB A4 HEK293 cells were stained with Anti-STAB1 Reference Antibody (bexmarilimab) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC50=0.2417 ug/mL.

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Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	Functional assay, Kinetics (SPR), Kinetics (BLI), FACS, E, FTA
Primary Accession	Q9NY15
Reactivity	Human
Clonality	Monoclonal
Isotype	IgG4SP
Calculated MW	275482 Da

Additional Information
Target/Specificity	STAB1
Endotoxin	< 0.001EU/ µg,determined by LAL method.
Conjugation	Unconjugated
Expression system	CHO
Format	Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column.

For Research Use Only. Not For Use In Diagnostic Procedures.

Patent Notice: The variable region sequence of this antibody is derived from a published third-party patent. This product is manufactured independently as a Research Use Only (RUO) reagent and is not licensed, sponsored, or endorsed by the patent holder. It is intended solely for research purposes. Customers considering any commercial, diagnostic, or therapeutic use should independently evaluate freedom-to-operate with respect to relevant third-party patents.

Protein Information
Name	STAB1
Synonyms	FEEL1, KIAA0246
Function	Acts as a scavenger receptor for acetylated low density lipoprotein. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. When inhibited in endothelial tube formation assays, there is a marked decrease in cell-cell interactions, suggesting a role in angiogenesis. Involved in the delivery of newly synthesized CHID1/SI-CLP from the biosynthetic compartment to the endosomal/lysosomal system.
Cellular Location	Membrane; Single-pass type I membrane protein
Tissue Location	High levels found in spleen, lymph node, liver and placenta. Also expressed in endothelial cells

Research Areas

Application Protocols

Provided below are standard protocols that you may find useful for product applications.

Western Blot Protocol

Blocking Peptides Protocol

Dot Blot Protocol

Immunohistochemistry Protocol

Immunofluorescence Protocol

Immunoprecipitation Protocol

Flow Cytomety Protocol

Cell Culture Protocol