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>   首页   >   产品   >   一抗   >   基因重组   >   Anti-FGF23 Reference Antibody (burosumab)   

Anti-FGF23 Reference Antibody (burosumab)

Recombinant Antibody

     
  • 1 - Anti-FGF23 Reference Antibody (burosumab) APR10626
    Anti-FGF23 Reference Antibody (burosumab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%
  • 1 - Anti-FGF23 Reference Antibody (burosumab) APR10626
    The purity of Anti-FGF23 Reference Antibody (burosumab)is more than 95% ,determined by SEC-HPLC.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
FC, Kinetics, Animal Model
Primary Accession Q9GZV9
Reactivity Human
Clonality Monoclonal
Isotype IgG1
Calculated MW 27954 Da
Additional Information
Target/Specificity FGF23
Endotoxin < 0.001EU/ µg,determined by LAL method.
Conjugation Unconjugated
Expression system CHO Cell
Format Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column.
Protein Information
Name FGF23
Synonyms HYPF
Function Regulator of phosphate homeostasis (PubMed:11062477). Inhibits renal tubular phosphate transport by reducing SLC34A1 levels (PubMed:11409890). Up-regulates EGR1 expression in the presence of KL (By similarity). Acts directly on the parathyroid to decrease PTH secretion (By similarity). Regulator of vitamin-D metabolism (PubMed:15040831). Negatively regulates osteoblast differentiation and matrix mineralization (PubMed:18282132).
Cellular Location Secreted. Note=Secretion is dependent on O-glycosylation
Tissue Location Expressed in osteogenic cells particularly during phases of active bone remodeling. In adult trabecular bone, expressed in osteocytes and flattened bone-lining cells (inactive osteoblasts)
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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