Anti-PLAUR / uPAR / CD87 Reference Antibody (ATN-658)
Recombinant Antibody
- 产品详情
- 实验流程
Application ![]()
| FC, Kinetics, Animal Model |
---|---|
Primary Accession | Q03405 |
Reactivity | Human, Mouse |
Clonality | Monoclonal |
Isotype | IgG1 |
Calculated MW | 36978 Da |
Target/Specificity | PLAUR / uPAR / CD87 |
---|---|
Endotoxin | < 0.001EU/ µg,determined by LAL method. |
Conjugation | Unconjugated |
Expression system | CHO Cell |
Format | Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column. |
Name | PLAUR |
---|---|
Synonyms | MO3, UPAR |
Function | Acts as a receptor for urokinase plasminogen activator (PubMed:15677461). Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form. |
Cellular Location | Cell membrane. Cell projection, invadopodium membrane Note=Colocalized with FAP (seprase) preferentially at the cell surface of invadopodia membrane in a cytoskeleton-, integrin- and vitronectin- dependent manner. [Isoform 2]: Secreted {ECO:0000250|UniProtKB:P49616} |
Tissue Location | Expressed in neurons of the rolandic area of the brain (at protein level). Expressed in the brain |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.

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Cat# APR11013