ARTS-1 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant ARTS-1.
- 产品详情
- 实验流程
- 背景知识
Application ![]()
| WB, E |
---|---|
Primary Accession | Q9NZ08 |
Other Accession | BC030775 |
Reactivity | Human |
Host | mouse |
Clonality | monoclonal |
Isotype | IgG1 Kappa |
Clone Names | 4H8 |
Calculated MW | 107235 Da |
Gene ID | 51752 |
---|---|
Other Names | Endoplasmic reticulum aminopeptidase 1, 3411-, ARTS-1, Adipocyte-derived leucine aminopeptidase, A-LAP, Aminopeptidase PILS, Puromycin-insensitive leucyl-specific aminopeptidase, PILS-AP, Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator, ERAP1, APPILS, ARTS1, KIAA0525 |
Target/Specificity | ARTS-1 (AAH30775, 832 a.a. ~ 941 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
Dilution | WB~~1:500~1000 E~~N/A |
Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
Precautions | ARTS-1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Aminopeptidases play a role in the metabolism of several peptides that may be involved in blood pressure and the pathogenesis of essential hypertension (MIM 145500). Adipocyte-derived leucine aminopeptidase (ALAP) is a member of the M1 family of zinc metallopeptidases.
REFERENCES
Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Serum cytokine receptors in ankylosing spondylitis: relationship to inflammatory markers and endoplasmic reticulum aminopeptidase polymorphisms. Haroon N, et al. J Rheumatol, 2010 Sep. PMID 20595269.Placental leucine aminopeptidase efficiently generates mature antigenic peptides in vitro but in patterns distinct from endoplasmic reticulum aminopeptidase 1. Georgiadou D, et al. J Immunol, 2010 Aug 1. PMID 20592285.Distinct molecular mechanisms leading to deficient expression of ER-resident aminopeptidases in melanoma. Kamphausen E, et al. Cancer Immunol Immunother, 2010 Aug. PMID 20419298.Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.

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