癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
DCPS Antibody (monoclonal) (M03)
Mouse monoclonal antibody raised against a full length recombinant DCPS.
- 产品详情
- 实验流程
Application 
| WB, IHC, E |
|---|---|
| Primary Accession | Q96C86 |
| Other Accession | BC014532 |
| Reactivity | Human, Rat |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG2a Kappa |
| Clone Names | 3E6 |
| Calculated MW | 38609 Da |
| Gene ID | 28960 |
|---|---|
| Other Names | m7GpppX diphosphatase, DCS-1, Decapping scavenger enzyme, Hint-related 7meGMP-directed hydrolase, Histidine triad nucleotide-binding protein 5, Histidine triad protein member 5, HINT-5, Scavenger mRNA-decapping enzyme DcpS, DCPS, DCS1, HINT5 |
| Target/Specificity | DCPS (AAH14532, 1 a.a. ~ 337 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 IHC~~1:100~500 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | DCPS Antibody (monoclonal) (M03) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Proteomic approach to the identification of novel delta-lactoferrin target genes: Characterization of DcpS, an mRNA scavenger decapping enzyme. Mariller C, et al. Biochimie, 2009 Jan. PMID 18725266.Mechanistic and kinetic analysis of the DcpS scavenger decapping enzyme. Liu SW, et al. J Biol Chem, 2008 Jun 13. PMID 18441014.DcpS scavenger decapping enzyme can modulate pre-mRNA splicing. Shen V, et al. RNA, 2008 Jun. PMID 18426921.Role of a novel dual flavin reductase (NR1) and an associated histidine triad protein (DCS-1) in menadione-induced cytotoxicity. Kwa?nicka-Crawford DA, et al. Biochem Biophys Res Commun, 2005 Oct 21. PMID 16140270.Crystal structures of human DcpS in ligand-free and m7GDP-bound forms suggest a dynamic mechanism for scavenger mRNA decapping. Chen N, et al. J Mol Biol, 2005 Apr 8. PMID 15769464.
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