癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
DCUN1D1 Antibody (monoclonal) (M02)
Mouse monoclonal antibody raised against a partial recombinant DCUN1D1.
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | Q96GG9 |
| Other Accession | NM_020640 |
| Reactivity | Human, Mouse, Rat |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG2b Kappa |
| Clone Names | 4B5 |
| Calculated MW | 30124 Da |
| Gene ID | 54165 |
|---|---|
| Other Names | DCN1-like protein 1, DCUN1 domain-containing protein 1, Defective in cullin neddylation protein 1-like protein 1, Squamous cell carcinoma-related oncogene, DCUN1D1, DCUN1L1, RP42, SCCRO |
| Target/Specificity | DCUN1D1 (NP_065691, 1 a.a. ~ 89 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | DCUN1D1 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
DCUN1D1 is a risk factor for frontotemporal lobar degeneration. Villa C, et al. Eur J Neurol, 2009 Jul. PMID 19473369.SCCRO (DCUN1D1) induces extracellular matrix invasion by activating matrix metalloproteinase 2. O-charoenrat P, et al. Clin Cancer Res, 2008 Nov 1. PMID 18980971.SCCRO (DCUN1D1) is an essential component of the E3 complex for neddylation. Kim AY, et al. J Biol Chem, 2008 Nov 28. PMID 18826954.Squamous cell carcinoma related oncogene/DCUN1D1 is highly conserved and activated by amplification in squamous cell carcinomas. Sarkaria I, et al. Cancer Res, 2006 Oct 1. PMID 17018598.Towards a proteome-scale map of the human protein-protein interaction network. Rual JF, et al. Nature, 2005 Oct 20. PMID 16189514.
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