癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
DNER Antibody (monoclonal) (M03)
Mouse monoclonal antibody raised against a partial recombinant DNER.
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | Q8NFT8 |
| Other Accession | NM_139072 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG3 Kappa |
| Clone Names | 4E9 |
| Calculated MW | 78475 Da |
| Gene ID | 92737 |
|---|---|
| Other Names | Delta and Notch-like epidermal growth factor-related receptor, DNER, BET |
| Target/Specificity | DNER (NP_620711, 368 a.a. ~ 476 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | DNER Antibody (monoclonal) (M03) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Polarized targeting of DNER into dendritic plasma membrane in hippocampal neurons depends on endocytosis. Kurisu J, et al. J Neurochem, 2010 Jun. PMID 20367751.New genetic associations detected in a host response study to hepatitis B vaccine. Davila S, et al. Genes Immun, 2010 Apr. PMID 20237496.DNER modulates adipogenesis of human adipose tissue-derived mesenchymal stem cells via regulation of cell proliferation. Park JR, et al. Cell Prolif, 2010 Feb. PMID 20070733.Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry. Ramachandran P, et al. J Proteome Res, 2006 Jun. PMID 16740002.Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560.
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