癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
ELF3 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant ELF3.
- 产品详情
- 实验流程
Application 
| WB, E |
|---|---|
| Primary Accession | P78545 |
| Other Accession | BC003569 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | monoclonal |
| Isotype | IgG1 Kappa |
| Clone Names | 1D8 |
| Calculated MW | 41454 Da |
| Gene ID | 1999 |
|---|---|
| Other Names | ETS-related transcription factor Elf-3, E74-like factor 3, Epithelial-restricted with serine box, Epithelium-restricted Ets protein ESX, Epithelium-specific Ets transcription factor 1, ESE-1, ELF3 (HGNC:3318) |
| Target/Specificity | ELF3 (AAH03569, 262 a.a. ~ 371 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | ELF3 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
ESE-1/EGR-1 pathway plays a role in tolfenamic acid-induced apoptosis in colorectal cancer cells. Lee SH, et al. Mol Cancer Ther, 2008 Dec. PMID 19074849.Regulation of epithelium-specific Ets-like factors ESE-1 and ESE-3 in airway epithelial cells: potential roles in airway inflammation. Wu J, et al. Cell Res, 2008 Jun. PMID 18475289.ESE-1 inhibits the invasion of oral squamous cell carcinoma in conjunction with MMP-9 suppression. Iwai S, et al. Oral Dis, 2008 Mar. PMID 18302674.ESE-1 is a potent repressor of type II collagen gene (COL2A1) transcription in human chondrocytes. Peng H, et al. J Cell Physiol, 2008 May. PMID 18044710.Toward a confocal subcellular atlas of the human proteome. Barbe L, et al. Mol Cell Proteomics, 2008 Mar. PMID 18029348.
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