癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
FOXF2 Antibody (monoclonal) (M08)
Mouse monoclonal antibody raised against a partial recombinant FOXF2.
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, IF, E |
|---|---|
| Primary Accession | Q12947 |
| Other Accession | NM_001452 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG2b Kappa |
| Clone Names | 3D11 |
| Calculated MW | 45993 Da |
| Gene ID | 2295 |
|---|---|
| Other Names | Forkhead box protein F2, Forkhead-related activator 2, FREAC-2, Forkhead-related protein FKHL6, Forkhead-related transcription factor 2, FOXF2, FKHL6, FREAC2 |
| Target/Specificity | FOXF2 (NP_001443, 346 a.a. ~ 443 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 IF~~1:50~200 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | FOXF2 Antibody (monoclonal) (M08) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
FOXF2 encodes forkhead box F2, one of many human homologues of the Drosophila melanogaster transcription factor forkhead. FOXF2 is expressed in lung and placenta, and has been shown to transcriptionally activate several lung-specific genes.
REFERENCES
Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. Jugessur A, et al. PLoS One, 2010 Jul 9. PMID 20634891.The FOXF2 pathway in the human prostate stroma. van der Heul-Nieuwenhuijsen L, et al. Prostate, 2009 Oct 1. PMID 19562724.Mutation analysis of FOXF2 in patients with disorders of sex development (DSD) in combination with cleft palate. Jochumsen U, et al. Sex Dev, 2008. PMID 19276632.Gene expression of forkhead transcription factors in the normal and diseased human prostate. van der Heul-Nieuwenhuijsen L, et al. BJU Int, 2009 Jun. PMID 19220249.Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening. Wu C, et al. Proteomics, 2007 Jun. PMID 17474147.
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