癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
HPX Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant HPX.
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, IP, E |
|---|---|
| Primary Accession | P02790 |
| Other Accession | BC005395 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG2b Kappa |
| Clone Names | 3A9-1A9 |
| Calculated MW | 51676 Da |
| Gene ID | 3263 |
|---|---|
| Other Names | Hemopexin, Beta-1B-glycoprotein, HPX |
| Target/Specificity | HPX (AAH05395, 1 a.a. ~ 254 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 IP~~N/A E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | HPX Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This gene encodes a plasma glycoprotein that binds heme with high affinity. The encoded protein is an acute phase protein that transports heme from the plasma to the liver and may be involved in protecting cells from oxidative stress.
REFERENCES
Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.MMP20 hemopexin domain mutation in amelogenesis imperfecta. Lee SK, et al. J Dent Res, 2010 Jan. PMID 19966041.Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Talmud PJ, et al. Am J Hum Genet, 2009 Nov. PMID 19913121.Proteomics-derived cerebrospinal fluid markers of autopsy-confirmed Alzheimer's disease. Roher AE, et al. Biomarkers, 2009 Nov. PMID 19863188.Chromatographically distinguishable heme insertion isoforms of human hemopexin. Mauk MR, et al. Biochemistry, 2007 Dec 25. PMID 18044975.
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