癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
IGSF8 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant IGSF8.
- 产品详情
- 实验流程
Application 
| E |
|---|---|
| Primary Accession | Q969P0 |
| Other Accession | BC004108 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG1 Kappa |
| Clone Names | 1E5 |
| Calculated MW | 65034 Da |
| Gene ID | 93185 |
|---|---|
| Other Names | Immunoglobulin superfamily member 8, IgSF8, CD81 partner 3, Glu-Trp-Ile EWI motif-containing protein 2, EWI-2, Keratinocytes-associated transmembrane protein 4, KCT-4, LIR-D1, Prostaglandin regulatory-like protein, PGRL, CD316, IGSF8, CD81P3, EWI2, KCT4 |
| Target/Specificity | IGSF8 (AAH04108, 220 a.a. ~ 322 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | IGSF8 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Glioblastoma inhibition by cell surface immunoglobulin protein EWI-2, in vitro and in vivo. Kolesnikova TV, et al. Neoplasia, 2009 Jan. PMID 19107234.The CD81 partner EWI-2wint inhibits hepatitis C virus entry. Rocha-Perugini V, et al. PLoS One, 2008 Apr 2. PMID 18382656.EWI-2/CD316 is an inducible receptor of HSPA8 on human dendritic cells. Kettner S, et al. Mol Cell Biol, 2007 Nov. PMID 17785435.EWI-2 and EWI-F link the tetraspanin web to the actin cytoskeleton through their direct association with ezrin-radixin-moesin proteins. Sala-Vald?s M, et al. J Biol Chem, 2006 Jul 14. PMID 16690612.Contrasting effects of EWI proteins, integrins, and protein palmitoylation on cell surface CD9 organization. Yang XH, et al. J Biol Chem, 2006 May 5. PMID 16537545.
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