IL1B Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant IL1B.
- 产品详情
- 实验流程
- 背景知识
Application ![]()
| WB, IF, IP, E |
---|---|
Primary Accession | P01584 |
Other Accession | BC008678 |
Reactivity | Human |
Host | mouse |
Clonality | monoclonal |
Isotype | IgG2b Kappa |
Clone Names | 2A8 |
Calculated MW | 30748 Da |
Gene ID | 3553 |
---|---|
Other Names | Interleukin-1 beta, IL-1 beta, Catabolin, IL1B, IL1F2 |
Target/Specificity | IL1B (AAH08678, 170 a.a. ~ 269 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
Dilution | WB~~1:500~1000 IF~~1:50~200 IP~~N/A E~~N/A |
Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
Precautions | IL1B Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
REFERENCES
1.Upregulation of MMP-13 via Runx2 in the stromal cell of Giant Cell Tumor.Mak IW, Cowan RW, Popovic S, Colterjohn N, Singh G, Ghert M.Bone. 2009 Aug;45(2):377-86. Epub 2009 May 5.

终于等到您。ABCEPTA(百远生物)抗体产品。
点击下方“我要评价 ”按钮提交您的反馈信息,您的反馈和评价是我们最宝贵的财富之一,
我们将在1-3个工作日内处理您的反馈信息。
如有疑问,联系:0512-88856768 tech-china@abcepta.com.