癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KIAA1967 Antibody (monoclonal) (M04)
Mouse monoclonal antibody raised against a full length recombinant KIAA1967.
- 产品详情
- 实验流程
Application 
| WB, IF |
|---|---|
| Primary Accession | Q8N163 |
| Other Accession | BC018269 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG1 Kappa |
| Clone Names | 4E7 |
| Calculated MW | 102902 Da |
| Gene ID | 57805 |
|---|---|
| Other Names | Cell cycle and apoptosis regulator protein 2, Cell division cycle and apoptosis regulator protein 2, DBIRD complex subunit KIAA1967, Deleted in breast cancer gene 1 protein, DBC-1, DBC1, p30 DBC, CCAR2, DBC1, KIAA1967 |
| Target/Specificity | KIAA1967 (AAH18269, 5 a.a. ~ 365 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 IF~~1:50~200 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | KIAA1967 Antibody (monoclonal) (M04) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Identification of DBC1 as a transcriptional repressor for BRCA1. Hiraike H, et al. Br J Cancer, 2010 Mar 16. PMID 20160719.Deleted in breast cancer-1 regulates SIRT1 activity and contributes to high-fat diet-induced liver steatosis in mice. Escande C, et al. J Clin Invest, 2010 Feb 1. PMID 20071779.p30 DBC is a potential regulator of tumorigenesis. Kim JE, et al. Cell Cycle, 2009 Sep 15. PMID 19657230.Expression of DBC1 and SIRT1 is associated with poor prognosis of gastric carcinoma. Cha EJ, et al. Clin Cancer Res, 2009 Jul 1. PMID 19509139.Inhibition of SUV39H1 methyltransferase activity by DBC1. Li Z, et al. J Biol Chem, 2009 Apr 17. PMID 19218236.
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