癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
MAML2 Antibody (monoclonal) (M03)
Mouse monoclonal antibody raised against a partial recombinant MAML2.
- 产品详情
- 实验流程
Application 
| WB, E |
|---|---|
| Primary Accession | Q8IZL2 |
| Other Accession | NM_032427 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG2a Kappa |
| Clone Names | 4A1 |
| Calculated MW | 125197 Da |
| Gene ID | 84441 |
|---|---|
| Other Names | Mastermind-like protein 2, Mam-2, MAML2, KIAA1819 |
| Target/Specificity | MAML2 (NP_115803, 796 a.a. ~ 894 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | MAML2 Antibody (monoclonal) (M03) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
A reappraisal of the MECT1/MAML2 translocation in salivary mucoepidermoid carcinomas. Seethala RR, et al. Am J Surg Pathol, 2010 Aug. PMID 20588178.Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.Clinicopathological significance of the CRTC3-MAML2 fusion transcript in mucoepidermoid carcinoma. Nakayama T, et al. Mod Pathol, 2009 Dec. PMID 19749740.Prognostic significance of p27Kip1, Ki-67, and CRTC1-MAML2 fusion transcript in mucoepidermoid carcinoma: a molecular and clinicopathologic study of 101 cases. Miyabe S, et al. J Oral Maxillofac Surg, 2009 Jul. PMID 19531414.A link between the expression of the stem cell marker HMGA2, grading, and the fusion CRTC1-MAML2 in mucoepidermoid carcinoma. Fehr A, et al. Genes Chromosomes Cancer, 2009 Sep. PMID 19521953.
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