癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
PASD1 Antibody (monoclonal) (M06)
Mouse monoclonal antibody raised against a full length recombinant PASD1.
- 产品详情
- 实验流程
- 背景知识
Application 
| WB |
|---|---|
| Primary Accession | Q8IV76 |
| Other Accession | NM_173493 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG2b Kappa |
| Clone Names | 1G12 |
| Calculated MW | 87428 Da |
| Gene ID | 139135 |
|---|---|
| Other Names | PAS domain-containing protein 1, Cancer/testis antigen 63, CT63, OX-TES-1, PASD1 |
| Target/Specificity | PASD1 (NP_775764, 1 a.a. ~ 100 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | PASD1 Antibody (monoclonal) (M06) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This gene encodes a protein that is thought to function as a transcription factor. The protein is a cancer-associated antigen that can stimulate autologous T-cell responses, and it is therefore considered to be a potential immunotherapeutic target for the treatment of various hematopoietic malignancies, including diffuse large B-cell lymphoma.
REFERENCES
Elevated expression levels of testis-specific genes TEX101 and SPATA19 in basal cell carcinoma and their correlation with clinical and pathological features. Ghafouri-Fard S, et al. Br J Dermatol, 2010 Apr. PMID 19886887.Cytolytic T-cell response to the PASD1 cancer testis antigen in patients with diffuse large B-cell lymphoma. Ait-Tahar K, et al. Br J Haematol, 2009 Aug. PMID 19552722.Toward a confocal subcellular atlas of the human proteome. Barbe L, et al. Mol Cell Proteomics, 2008 Mar. PMID 18029348.PASD1 is a potential multiple myeloma-associated antigen. Sahota SS, et al. Blood, 2006 Dec 1. PMID 17114574.PASD1, a DLBCL-associated cancer testis antigen and candidate for lymphoma immunotherapy. Cooper CD, et al. Leukemia, 2006 Dec. PMID 17024112.
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