癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
PLXDC1 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant PLXDC1.
- 产品详情
- 实验流程
Application 
| WB, E |
|---|---|
| Primary Accession | Q8IUK5 |
| Other Accession | NM_020405 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG2b Kappa |
| Clone Names | 4B10 |
| Calculated MW | 55760 Da |
| Gene ID | 57125 |
|---|---|
| Other Names | Plexin domain-containing protein 1, Tumor endothelial marker 3, Tumor endothelial marker 7, PLXDC1, TEM3, TEM7 |
| Target/Specificity | PLXDC1 (NP_065138, 313 a.a. ~ 421 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | PLXDC1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.Preferential expression of the secreted and membrane forms of tumor endothelial marker 7 transcripts in osteosarcoma. Halder C, et al. Anticancer Res, 2009 Nov. PMID 20032373.TEM7 (PLXDC1) in neovascular endothelial cells of fibrovascular membranes from patients with proliferative diabetic retinopathy. Yamaji Y, et al. Invest Ophthalmol Vis Sci, 2008 Jul. PMID 18316703.High expression of tumor endothelial marker 7 is associated with metastasis and poor survival of patients with osteogenic sarcoma. Fuchs B, et al. Gene, 2007 Sep 15. PMID 17560052.Identification of the basement membrane protein nidogen as a candidate ligand for tumor endothelial marker 7 in vitro and in vivo. Lee HK, et al. FEBS Lett, 2006 Apr 17. PMID 16574105.
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