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>   首页   >   产品   >   一抗   >   癌症   >   PRPS2 Antibody (monoclonal) (M02)   

PRPS2 Antibody (monoclonal) (M02)

Mouse monoclonal antibody raised against a partial recombinant PRPS2.

     
  • 1 - PRPS2 Antibody (monoclonal) (M02) AT3444a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.84 KDa) .
  • 1 - PRPS2 Antibody (monoclonal) (M02) AT3444a
    Western Blot analysis of PRPS2 expression in transfected 293T cell line by PRPS2 monoclonal antibody (M02), clone 4C1.

    Lane 1: PRPS2 transfected lysate(34.8 KDa).
    Lane 2: Non-transfected lysate.
  • 1 - PRPS2 Antibody (monoclonal) (M02) AT3444a
    Western blot analysis of PRPS2 over-expressed 293 cell line, cotransfected with PRPS2 Validated Chimera RNAi ( (Cat # AT3444a )
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession P11908
Other Accession NM_002765
Reactivity Human
Host mouse
Clonality monoclonal
Isotype IgG2a Kappa
Clone Names 4C1
Calculated MW 34769 Da
Additional Information
Gene ID 5634
Other Names Ribose-phosphate pyrophosphokinase 2, PPRibP, Phosphoribosyl pyrophosphate synthase II, PRS-II, PRPS2
Target/Specificity PRPS2 (NP_002756, 160 a.a. ~ 269 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsPRPS2 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

This gene encodes a phosphoribosyl pyrophosphate synthetase that plays a central role in the synthesis of purines and pyrimidines. The encoded protein catalyzes the synthesis of 5-phosphoribosyl 1-pyrophosphate from ATP and D-ribose 5-phosphate. Alternate splicing results in multiple transcript variants.

REFERENCES

Direct role of nucleotide metabolism in C-MYC-dependent proliferation of melanoma cells. Mannava S, et al. Cell Cycle, 2008 Aug. PMID 18677108.[Increased activity of PRPP synthetase] Iizasa T. Nippon Rinsho, 2008 Apr. PMID 18409517.Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.

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