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PRPS2 Antibody (Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - PRPS2 Antibody (Center) AP16421c
    PRPS2 Antibody (Center) (Cat. #AP16421c) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the PRPS2 antibody detected the PRPS2 protein (arrow).
  • 1 - PRPS2 Antibody (Center) AP16421c
    Western blot analysis of PRPS2 (arrow) using rabbit polyclonal PRPS2 Antibody (Center) (Cat. #AP16421c). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PRPS2 gene.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession P11908
Other Accession Q7ZXC9, P09330, Q9CS42, Q4R4R7, P60892, Q9D7G0, Q4R4U3, P60891, Q2HJ58, P38063, P38620, NP_001034180.1
Reactivity Human
Predicted Yeast, Bovine, Monkey, Mouse, Rat, Xenopus
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 34769 Da
Antigen Region 77-106 aa
Additional Information
Gene ID 5634
Other Names Ribose-phosphate pyrophosphokinase 2, PPRibP, Phosphoribosyl pyrophosphate synthase II, PRS-II, PRPS2
Target/Specificity This PRPS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 77-106 amino acids from the Central region of human PRPS2.
Dilution WB~~1:1000
E~~Use at an assay dependent concentration.
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPRPS2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PRPS2
Function Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

PRPS2 is a phosphoribosyl pyrophosphate synthetase that plays a central role in the synthesis of purines and pyrimidines. The encoded protein catalyzes the synthesis of 5-phosphoribosyl 1-pyrophosphate from ATP and D-ribose 5-phosphate. Alternate splicing results in multiple transcript variants.

REFERENCES

Mannava, S., et al. Cell Cycle 7(15):2392-2400(2008)
Tatibana, M., et al. Adv. Enzyme Regul. 35, 229-249 (1995) :
Dawson, S.J., et al. J. Infect. 24(3):317-320(1992)
Ishizuka, T., et al. Biochim. Biophys. Acta 1130(2):139-148(1992)
Becker, M.A., et al. Genomics 8(3):555-561(1990)

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