癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
RASSF8 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant RASSF8.
- 产品详情
- 实验流程
Application 
| WB, IHC, IF, IP, E |
|---|---|
| Primary Accession | Q8NHQ8 |
| Other Accession | NM_007211 |
| Reactivity | Human, Mouse |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG2a Kappa |
| Clone Names | 2G1 |
| Calculated MW | 48327 Da |
| Gene ID | 11228 |
|---|---|
| Other Names | Ras association domain-containing protein 8, Carcinoma-associated protein HOJ-1, RASSF8, C12orf2 |
| Target/Specificity | RASSF8 (NP_009142, 40 a.a. ~ 137 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 IHC~~1:100~500 IF~~1:50~200 IP~~N/A E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | RASSF8 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
The RASSF8 candidate tumor suppressor inhibits cell growth and regulates the Wnt and NF-kappaB signaling pathways. Lock FE, et al. Oncogene, 2010 Jul 29. PMID 20514026.Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.Common polymorphisms in D12S1034 flanking genes RASSF8 and BHLHB3 are not associated with lung adenocarcinoma risk. Falvella FS, et al. Lung Cancer, 2007 Apr. PMID 17194498.Identification of RASSF8 as a candidate lung tumor suppressor gene. Falvella FS, et al. Oncogene, 2006 Jun 29. PMID 16462760.Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560.
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