癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
RHOT1 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant RHOT1.
- 产品详情
- 实验流程
Application 
| WB, E |
|---|---|
| Primary Accession | Q8IXI2 |
| Other Accession | NM_018307 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG1 Kappa |
| Clone Names | 4H4 |
| Calculated MW | 70784 Da |
| Gene ID | 55288 |
|---|---|
| Other Names | Mitochondrial Rho GTPase 1, MIRO-1, hMiro-1, 365-, Rac-GTP-binding protein-like protein, Ras homolog gene family member T1, RHOT1, ARHT1 |
| Target/Specificity | RHOT1 (NP_060777, 483 a.a. ~ 580 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | RHOT1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
1.GTPase of the immune-associated nucleotide-binding protein 5 (GIMAP5) regulates calcium influx in T lymphocytes by promoting mitochondrial calcium accumulation.Chen XL, Serrano D, Mayhue M, Wieden HJ, Stankova J, Boulay G, Ilangumaran S, Ramanathan S.Biochem J. 2012 Oct 26. [Epub ahead of print]2.N-acetylglucosamine transferase is an integral component of a kinesin-directed mitochondrial trafficking complex.Pozo KB, Stephenson FA.Biochim Biophys Acta. 2010 Oct 27. [Epub ahead of print]3.GTPase dependent recruitment of Grif-1 by Miro1 regulates mitochondrial trafficking in hippocampal neurons.Macaskill AF, Brickley K, Stephenson FA, Kittler JT.Mol Cell Neurosci. 2009 Mar;40(3):301-12. Epub 2008 Dec 3.
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