癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
RNASEH1 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant RNASEH1.
- 产品详情
- 实验流程
Application 
| WB, E |
|---|---|
| Primary Accession | O60930 |
| Other Accession | NM_002936 |
| Reactivity | Human, Rat |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG2a Kappa |
| Clone Names | 5D10 |
| Calculated MW | 32064 Da |
| Gene ID | 246243 |
|---|---|
| Other Names | Ribonuclease H1, RNase H1, Ribonuclease H type II, RNASEH1, RNH1 |
| Target/Specificity | RNASEH1 (NP_002927, 189 a.a. ~ 286 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | RNASEH1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Specific recognition of RNA/DNA hybrid and enhancement of human RNase H1 activity by HBD. Nowotny M, et al. EMBO J, 2008 Apr 9. PMID 18337749.Structure of human RNase H1 complexed with an RNA/DNA hybrid: insight into HIV reverse transcription. Nowotny M, et al. Mol Cell, 2007 Oct 26. PMID 17964265.Human RNase H1 discriminates between subtle variations in the structure of the heteroduplex substrate. Lima WF, et al. Mol Pharmacol, 2007 Jan. PMID 17028158.The positional influence of the helical geometry of the heteroduplex substrate on human RNase H1 catalysis. Lima WF, et al. Mol Pharmacol, 2007 Jan. PMID 17028157.Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries. Otsuki T, et al. DNA Res, 2005. PMID 16303743.
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