癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
SFPQ Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant SFPQ.
- 产品详情
- 实验流程
Application 
| WB, IF, E |
|---|---|
| Primary Accession | P23246 |
| Other Accession | NM_005066 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG2a Kappa |
| Clone Names | 3B10 |
| Calculated MW | 76149 Da |
| Gene ID | 6421 |
|---|---|
| Other Names | Splicing factor, proline- and glutamine-rich, 100 kDa DNA-pairing protein, hPOMp100, DNA-binding p52/p100 complex, 100 kDa subunit, Polypyrimidine tract-binding protein-associated-splicing factor, PSF, PTB-associated-splicing factor, SFPQ, PSF |
| Target/Specificity | SFPQ (NP_005057, 269 a.a. ~ 361 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 IF~~1:50~200 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | SFPQ Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
hnRNP M interacts with PSF and p54(nrb) and co-localizes within defined nuclear structures. Marko M, et al. Exp Cell Res, 2010 Feb 1. PMID 19874820.Identification and characterisation of a novel GHR defect disrupting the polypyrimidine tract and resulting in GH insensitivity. David A, et al. Eur J Endocrinol, 2010 Jan. PMID 19812236.Melanotic Xp11 translocation renal cancer: a case with PSF-TFE3 gene fusion and up-regulation of melanogenetic transcripts. Chang IW, et al. Am J Surg Pathol, 2009 Dec. PMID 19809274.Human PSF binds to RAD51 and modulates its homologous-pairing and strand-exchange activities. Morozumi Y, et al. Nucleic Acids Res, 2009 Jul. PMID 19447914.Interplay between polypyrimidine tract binding protein-associated splicing factor and human myometrial progesterone receptors. Tyson-Capper AJ, et al. J Mol Endocrinol, 2009 Jul. PMID 19339282.
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