癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
SH3RF2 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant SH3RF2.
- 产品详情
- 实验流程
Application 
| WB, E |
|---|---|
| Primary Accession | Q8TEC5 |
| Other Accession | NM_152550 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG2a Kappa |
| Clone Names | 4E11 |
| Calculated MW | 79320 Da |
| Gene ID | 153769 |
|---|---|
| Other Names | Putative E3 ubiquitin-protein ligase SH3RF2, 632-, Heart protein phosphatase 1-binding protein, HEPP1, Protein phosphatase 1 regulatory subunit 39, RING finger protein 158, SH3 domain-containing RING finger protein 2, SH3RF2, PPP1R39, RNF158 |
| Target/Specificity | SH3RF2 (NP_660205, 640 a.a. ~ 729 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | SH3RF2 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
1.SH3RF2 Functions as an Oncogene by Mediating PAK4 Protein Stability.Kim TW, Kang YK, Park ZY, Kim YH, Hong SW, Su JO, Sohn HA, Yang SJ, Jang YJ, Lee DC, Kim SY, Yoo HS, Kim E, Yeom YI, Park KCCarcinogenesis. 2013 Oct 15.2.Sh3rf2/POSHER promotes cell survival by RING-mediated proteasomal degradation of the JNK scaffold POSH.Wilhelm M, Kukekov NV, Schmit TL, Biagas KV, Sproul AA, Gire S, Maes ME, Xu Z, Greene LA.J Biol Chem. 2011 Nov 28.
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