癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
SPRR3 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant SPRR3.
- 产品详情
- 实验流程
Application 
| WB, IHC, E |
|---|---|
| Primary Accession | Q9UBC9 |
| Other Accession | BC017802 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG3 Kappa |
| Clone Names | 4A12 |
| Calculated MW | 18154 Da |
| Gene ID | 6707 |
|---|---|
| Other Names | Small proline-rich protein 3, 22 kDa pancornulin, Cornifin beta, Esophagin, SPRR3, SPRC |
| Target/Specificity | SPRR3 (AAH17802, 1 a.a. ~ 161 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 IHC~~1:100~500 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | SPRR3 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Characterization of two isoforms of human SPRR3 from saliva of preterm human newborn and autoptic fetal oral mucosa, parotid and submandibular gland samples. Manconi B, et al. Biochem Biophys Res Commun, 2010 Jul 30. PMID 20599699.Biomechanical stress induces novel arterial intima-enriched genes: implications for vascular adaptation to stress. Pyle AL, et al. Cardiovasc Pathol, 2010 Mar-Apr. PMID 19211270.Regulation of the atheroma-enriched protein, SPRR3, in vascular smooth muscle cells through cyclic strain is dependent on integrin alpha1beta1/collagen interaction. Pyle AL, et al. Am J Pathol, 2008 Nov. PMID 18832573.Association of psoriasis to PGLYRP and SPRR genes at PSORS4 locus on 1q shows heterogeneity between Finnish, Swedish and Irish families. Kainu K, et al. Exp Dermatol, 2009 Feb. PMID 18643845.Exogenous expression of Esophagin/SPRR3 attenuates the tumorigenicity of esophageal squamous cell carcinoma cells via promoting apoptosis. Zhang Y, et al. Int J Cancer, 2008 Jan 15. PMID 17935133.
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