癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
TPI1 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant TPI1.
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, E |
|---|---|
| Primary Accession | P60174 |
| Other Accession | BC007086 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG1 Kappa |
| Clone Names | 1D10-2E2 |
| Calculated MW | 26669 Da |
| Gene ID | 7167 |
|---|---|
| Other Names | Triosephosphate isomerase, TIM, Triose-phosphate isomerase, TPI1, TPI |
| Target/Specificity | TPI1 (AAH07086.1, 1 a.a. ~ 249 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | TPI1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This gene encodes an enzyme, consisting of two identical proteins, which catalyzes the isomerization of glyceraldehydes 3-phosphate (G3P) and dihydroxy-acetone phosphate (DHAP) in glycolysis and gluconeogenesis. Mutations in this gene are associated with triosephosphate isomerase deficiency. Pseudogenes have been identified on chromosomes 1, 4, 6 and 7. Alternative splicing results in multiple transcript variants.
REFERENCES
1.Impact of cisplatin administration on protein expression levels in renal cell carcinoma: A proteomic analysis.Vasko R, Mueller GA, von Jaschke AK, Asif AR, Dihazi H.Eur J Pharmacol. 2011 Sep 8.2.Proteomic Analysis of Butyrate Effects and Loss of Butyrate Sensitivity in HT29 Colorectal Cancer Cells.Fung KY, Lewanowitsch T, Henderson ST, Priebe I, Hoffmann P, Lockett T, Head R, Cosgrove LJ.J Proteome Res. 2009 Mar;8(3):1220-7.3.Proteome of human T lymphocytes with treatment of cyclosporine and polysaccharopeptide: Analysis of significant proteins that manipulate T cells proliferation and immunosuppression.Lee CL, Jiang PP, Sit WH, Wan JM.Int Immunopharmacol. 2007 Oct;7(10):1311-24. Epub 2007 Jun 19.
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