癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
RPL6 Antibody (N-term)
Purified Rabbit Polyclonal Antibody (Pab)
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- 实验流程
- 背景知识
Application 
| IHC-P, IF, FC, WB |
|---|---|
| Primary Accession | Q02878 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | polyclonal |
| Calculated MW | 32728 Da |
| Isotype | Rabbit IgG |
| Antigen Source | HUMAN |
| Gene ID | 6128 |
|---|---|
| Antigen Region | 2-35 aa |
| Other Names | 60S ribosomal protein L6, Neoplasm-related protein C140, Tax-responsive enhancer element-binding protein 107, TaxREB107, RPL6, TXREB1 |
| Dilution | IHC-P~~1:100~500 IF~~1:25 FC~~1:25 WB~~1:1000 |
| Target/Specificity | This RPL6 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 2-35amino acids from the N-terminal region of human RPL6. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | RPL6 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RPL6 |
|---|---|
| Synonyms | TXREB1 |
| Function | Component of the large ribosomal subunit (PubMed:12962325, PubMed:23636399, PubMed:25901680, PubMed:25957688, PubMed:32669547). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:12962325, PubMed:23636399, PubMed:25901680, PubMed:25957688, PubMed:32669547). |
| Cellular Location | Cytoplasm, cytosol. Cytoplasm Rough endoplasmic reticulum {ECO:0000250|UniProtKB:Q2YGT9} Note=Detected on cytosolic polysomes (PubMed:25957688). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity). {ECO:0000250|UniProtKB:Q2YGT9, ECO:0000269|PubMed:25957688} |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Specifically binds to domain C of the Tax-responsive enhancer element in the long terminal repeat of HTLV-I.
REFERENCES
Zaman G.J.R.,et al.Nucleic Acids Res. 21:1673-1673(1993).
Morita T.,et al.AIDS Res. Hum. Retroviruses 9:115-121(1993).
Kenmochi N.,et al.J. Hum. Genet. 45:290-293(2000).
Ohta K.,et al.J. Mol. Endocrinol. 12:85-92(1994).
Odintsova T.I.,et al.J. Protein Chem. 22:249-258(2003).
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