癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
SEMA4F Antibody (C-term)
Purified Rabbit Polyclonal Antibody (Pab)
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Application 
| WB |
|---|---|
| Primary Accession | O95754 |
| Other Accession | Q9Z143, Q9Z123 |
| Reactivity | Human, Rat |
| Predicted | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 83511 Da |
| Isotype | Rabbit IgG |
| Antigen Source | HUMAN |
| Gene ID | 10505 |
|---|---|
| Antigen Region | 695-709 aa |
| Other Names | Semaphorin-4F, Semaphorin-M, Sema M, Semaphorin-W, Sema W, SEMA4F, SEMAM, SEMAW |
| Dilution | WB~~1:1000 |
| Target/Specificity | This SEMA4F antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 695-709 amino acids from the C-terminal region of human SEMA4F. |
| Format | Purified polyclonal antibody supplied in PBS with 0.05% (V/V) Proclin 300. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SEMA4F Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | SEMA4F |
|---|---|
| Synonyms | SEMAM, SEMAW |
| Function | Probable cell surface receptor that regulates oligodendroglial precursor cell migration (By similarity). Might also regulate differentiation of oligodendroglial precursor cells (By similarity). Has growth cone collapse activity against retinal ganglion-cell axons (By similarity). |
| Cellular Location | Cell membrane; Single-pass type I membrane protein. Postsynaptic density {ECO:0000250|UniProtKB:Q9Z143}. Perikaryon {ECO:0000250|UniProtKB:Q9Z123}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q9Z123}. Note=Colocalizes with DLG4 at synapses {ECO:0000250|UniProtKB:Q9Z123} |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Has growth cone collapse activity against retinal ganglion-cell axons (By similarity).
REFERENCES
Encinas J.A.,et al.Proc. Natl. Acad. Sci. U.S.A. 96:2491-2496(1999).
Wiemann S.,et al.Genome Res. 11:422-435(2001).
Otsuki T.,et al.DNA Res. 12:117-126(2005).
Hillier L.W.,et al.Nature 434:724-731(2005).
Jang W.,et al.Submitted (MAR-1998) to the EMBL/GenBank/DDBJ databases.
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