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Mouse Hmga2 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
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  • 1 - Mouse Hmga2 Antibody (C-term) AW5498
    All lanes : Anti-Hmga2 Antibody (C-term) at 1:1000 dilution Lane 1: NIH/3T3 whole cell lysates Lane 2: HepG2 whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 12 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession P52927
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 11819 Da
Isotype Rabbit IgG
Antigen Source HUMAN
Additional Information
Gene ID 15364
Antigen Region 72-105 aa
Other Names High mobility group protein HMGI-C, High mobility group AT-hook protein 2, Hmga2, Hmgic
Dilution WB~~1:1000
Target/Specificity This Mouse Hmga2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 72-105 amino acids from the C-terminal region of Mouse Hmga2.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMouse Hmga2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Hmga2
Synonyms Hmgic
Function Functions as a transcriptional regulator. Functions in cell cycle regulation through CCNA2. Plays an important role in chromosome condensation during the meiotic G2/M transition of spermatocytes. Plays a role in postnatal myogenesis, is involved in satellite cell activation (PubMed:27446912). Positively regulates IGF2 expression through PLAG1 and in a PLAG1-independent manner (By similarity).
Cellular Location Nucleus.
Tissue Location Expressed in mitotic spermatogonia, meiotic spermatocytes, and postmeiotic round spermatids (at protein level) (PubMed:14668482). Expressed in embryonic myogenic progenitor cells (PubMed:27446912).
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

Functions as a transcriptional regulator. Functions in cell cycle regulation through CCNA2. Plays an important role in chromosome condensation during the meiotic G2/M transition of spermatocytes.

REFERENCES

Manfioletti G.,et al.Nucleic Acids Res. 19:6793-6797(1991).
Manfioletti G.,et al.Gene 167:249-253(1995).
Zhou X.,et al.Nucleic Acids Res. 24:4071-4077(1996).
Carninci P.,et al.Science 309:1559-1563(2005).
Di Agostino S.,et al.Mol. Biol. Cell 15:1224-1232(2004).

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