癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
4-1BBL/TNFSF9
- 产品详情
- 实验流程
| Primary Accession | P41273 |
|---|---|
| Species | Human |
| Sequence | Arg71-Glu254 |
| Purity | > 95% as analyzed by SDS-PAGE |
| Endotoxin Level | ≤ 1 EU/ µg of protein by LAL method |
| Expression System | E. coli |
| Formulation | Lyophilized from a 0.2 µm filtered solution in 20 mM Tris-HCl, 150 mM NaCl, pH 7.4. |
| Reconstitution | It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in distilled water up to 100 µg/ml. |
| Storage & Stability | Upon receiving, this product remains stable for up to 6 months at -70°C or -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4-7°C and up to 3 months at -20 °C or below. Avoid repeated freeze-thaw cycles. |
| Gene ID | 8744 |
|---|---|
| Other Names | Tumor necrosis factor ligand superfamily member 9, 4-1BB ligand, 4-1BBL, TNFSF9 |
| Target Background | Tumor necrosis factor ligand superfamily member 9(4-1BBL) is single-pass type II membrane protein which is a member of the the tumor necrosis factor family. 4 1BBL is a 254 amino acids cytokine that is expressed in brain, placenta, lung, skeletal muscle and kidney. TNFSF9 has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine may have a role in activation-induced cell death (AICD) and cognate interactions between T-cells and B-cells/macrophages. It has also been shown to be required for the optimal CD8 responses in CD8 T cells, and is thought to be involved in T cell-tumor cell interaction. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | TNFSF9 |
|---|---|
| Function | Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation- induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages. |
| Cellular Location | Membrane; Single-pass type II membrane protein. |
| Tissue Location | Expressed in brain, placenta, lung, skeletal muscle and kidney |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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