癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
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Mouse Monoclonal Antibody [Clone AE-1/AE-3]
Cytokeratin, pan (Epithelial Marker) Mouse Monoclonal Antibody [Clone AE-1/AE-3]
Purified Mouse Monoclonal Antibody
![1 - Cytokeratin, pan (Epithelial Marker)
Mouse Monoclonal Antibody [Clone AE-1/AE-3] AH10374](/assets/uploads/products/201506/AH10374_FC_1.jpg)
- 产品详情
- 实验流程
Application 
| IF, FC |
|---|---|
| Primary Accession | Q7Z794 |
| Other Accession | Q01546 |
| Reactivity | Human, Mouse, Rat, Rabbit, Monkey, Chicken, Dog, Bovine |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1, kappa + IgG1, kappa |
| Clone Names | AE-1/AE-3 |
| Calculated MW | 61901 Da |
| Gene ID | 374454 |
|---|---|
| Other Names | K1B; KRT1B; Keratin, type II cytoskeletal 1b; K77; CK-1B; Keratin 1B; Keratin-77; Cytokeratin-1B; Type-II Keratin Kb39 |
| Target/Specificity | Human epidermal keratin |
| Application Note | Flow Cytometry (0.5-1ug/million cells); Immunofluorescence (1-2ug/ml for 30 min at RT) (Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined. |
| Format | 0.5ml at 100ug/ml with BSA and azide |
| Storage | Store at 2 to 8°C.Antibody is stable for 24 months. |
| Precautions | Cytokeratin, pan (Epithelial Marker) Mouse Monoclonal Antibody [Clone AE-1/AE-3] is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | KRT77 (HGNC:20411) |
|---|---|
| Synonyms | KRT1B |
| Function | Structural component of intermediate filaments in epithelial cells of stratified epithelia. Assembles into heteropolymers with a type I keratin, forming keratin intermediate filament networks contributing to epithelial integrity. |
| Tissue Location | Expressed in skin.. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
1. Woodock-Mitchell J et. al. Journal of Cell Biology 1982;95:580-8.
2. Tseng SCG et. al. Cell 1982; 30361.
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