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OSMR antibody - middle region

Rabbit Polyclonal Antibody

     
  • 1 - OSMR antibody - middle region AI12677

    WB Suggested Anti-OSMR Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:312500
    Positive Control: 721_B cell lysate
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q99650
Other Accession NM_003999, NP_003990
Reactivity Human, Rabbit, Dog, Guinea Pig, Horse
Predicted Human, Rabbit, Dog, Guinea Pig, Horse
Host Rabbit
Clonality Polyclonal
Calculated MW 110509 Da
Additional Information
Gene ID 9180
Alias Symbol MGC150626, MGC150627, MGC75127, OSMRB, PLCA1
Other Names Oncostatin-M-specific receptor subunit beta, Interleukin-31 receptor subunit beta, IL-31 receptor subunit beta, IL-31R subunit beta, IL-31R-beta, IL-31RB, OSMR, OSMRB
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-OSMR antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsOSMR antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name OSMR
Synonyms OSMRB
Function Associates with IL31RA to form the IL31 receptor. Binds IL31 to activate STAT3 and possibly STAT1 and STAT5. Capable of transducing OSM-specific signaling events.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Expressed in keratinocytes (at protein level) (PubMed:21261663). Expressed at relatively high levels in all neural cells as well as fibroblast and epithelial cells (PubMed:8999038)
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

REFERENCES

Arita,K.,(2008)Am.J.Hum.Genet.82(1),73-80ReconstitutionandStorage:Forshorttermuse,storeat2-8Cupto1week.Forlongtermstorage,storeat-20Cinsmallaliquotstopreventfreeze-thawcycles.

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