癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
IL22RA2 Antibody - C-terminal region
Rabbit Polyclonal Antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | Q969J5 |
| Other Accession | NM_052962, NP_443194 |
| Reactivity | Human, Dog |
| Predicted | Human, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 30550 Da |
| Gene ID | 116379 |
|---|---|
| Alias Symbol | CRF2-10, CRF2-S1, CRF2X, IL-22BP, MGC150509, MGC150510 |
| Other Names | Interleukin-22 receptor subunit alpha-2, IL-22 receptor subunit alpha-2, IL-22R-alpha-2, IL-22RA2, Cytokine receptor class-II member 10, Cytokine receptor family 2 member 10, CRF2-10, Cytokine receptor family type 2, soluble 1, CRF2-S1, Interleukin-22-binding protein, IL-22BP, IL22BP, ZcytoR16, IL22RA2 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-IL22RA2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | IL22RA2 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | IL22RA2 |
|---|---|
| Function | Isoform 2 is a receptor for IL22. Binds to IL22, prevents interaction with the functional IL-22R complex and blocks the activity of IL22 (in vitro). May play an important role as an IL22 antagonist in the regulation of inflammatory responses. |
| Cellular Location | Secreted. |
| Tissue Location | Expressed in placenta, spleen, breast, skin and lung. Also detected in intestinal tract, testis, brain, heart and thymus. No expression found in prostate, bladder, kidney, ovary, muscle, bone marrow, liver and uterus. Isoform 1 is expressed only in placenta. Isoform 2 is expressed in placenta and breast and at lower level in spleen, skin, thymus and stomach |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Gruenberg B.H.,et al.Genes Immun. 2:329-334(2001).
Kotenko S.V.,et al.J. Immunol. 166:7096-7103(2001).
Dumoutier L.,et al.J. Immunol. 166:7090-7095(2001).
Xu W.,et al.Proc. Natl. Acad. Sci. U.S.A. 98:9511-9516(2001).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
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