癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
APOL1 Antibody
Purified Mouse Monoclonal Antibody
- 产品详情
- 实验流程
Application 
| WB, E |
|---|---|
| Primary Accession | O14791 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 1D4 |
| Isotype | IgG1 |
| Calculated MW | 43974 Da |
| Description | APOL1(apolipoprotein L, 1), also known as APOL, APO-L, APOL-I. Entrez Protein NP_001130012. It is a 395aa secreted high density lipoprotein which binds to apolipoprotein A-I. And is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. The apolipoprotein L gene family encodes six highly homologous proteins designated apoL-I to -VI. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Several different transcript variants encoding different isoforms have been found for this gene. |
| Immunogen | Purified recombinant fragment of APOL1 expressed in E. Coli. |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
| Gene ID | 8542 |
|---|---|
| Other Names | Apolipoprotein L1, Apolipoprotein L, Apo-L, ApoL, Apolipoprotein L-I, ApoL-I, APOL1, APOL |
| Dilution | WB~~1/500 - 1/2000 E~~N/A |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | APOL1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | APOL1 |
|---|---|
| Synonyms | APOL |
| Function | May play a role in lipid exchange and transport throughout the body. May participate in reverse cholesterol transport from peripheral cells to the liver. |
| Cellular Location | Secreted. |
| Tissue Location | Plasma. Found on APOA-I-containing high density lipoprotein (HDL3). Expressed in pancreas, lung, prostate, liver, placenta and spleen |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
1. Proc Natl Acad Sci U S A. 2007 Mar 6;104(10):4118-23. 2. J Lipid Res. 2005 Mar;46(3):469-74.
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