癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
ERMAP Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
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- 背景知识
Application 
| WB, E |
|---|---|
| Primary Accession | Q96PL5 |
| Other Accession | NP_001017922.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 52605 Da |
| Antigen Region | 69-95 aa |
| Gene ID | 114625 |
|---|---|
| Other Names | Erythroid membrane-associated protein, hERMAP, Radin blood group antigen, Scianna blood group antigen, ERMAP, RD, SC |
| Target/Specificity | This ERMAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-95 amino acids from the N-terminal region of human ERMAP. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ERMAP Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ERMAP |
|---|---|
| Synonyms | RD, SC |
| Function | Possible role as a cell-adhesion or receptor molecule of erythroid cells. |
| Cellular Location | Cell membrane; Single-pass type I membrane protein. Cytoplasm |
| Tissue Location | Expressed in erythroid-enriched bone marrow (at protein level). Highly expressed in bone marrow and to a lower extent in leukocytes, thymus, lymph node and spleen |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
The protein encoded by this gene is a cell surface transmembrane protein that may act as an erythroid cell receptor, possibly as a mediator of cell adhesion. Polymorphisms in this gene are responsible for the Scianna/Radin blood group system. Two transcript variants encoding the same protein have been found for this gene.
REFERENCES
Fuchisawa, A., et al. Immunohematology 25(1):18-19(2009)
Lin, L.D., et al. Zhongguo Shi Yan Xue Ye Xue Za Zhi 16(2):328-332(2008)
Flegel, W.A., et al. Transfusion 45(12):1940-1944(2005)
Hue-Roye, K., et al. Transfusion 45(2):245-247(2005)
Yan, L., et al. Immunohematology 21(1):10-14(2005)
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