CD34 Antibody (C-term)
Purified Rabbit Polyclonal Antibody (Pab)
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Application ![]()
| WB, FC, E |
---|---|
Primary Accession | P28906 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 40716 Da |
Gene ID | 947 |
---|---|
Other Names | Hematopoietic progenitor cell antigen CD34, CD34, CD34 |
Target/Specificity | This CD34 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 356-390 amino acids from the C-terminal region of human CD34. |
Dilution | WB~~1:1000 FC~~1:25 E~~Use at an assay dependent concentration. |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | CD34 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CD34 |
---|---|
Function | Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins. |
Cellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Location | Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.
REFERENCES
Simmons D.L.,et al.J. Immunol. 148:267-271(1992).
Satterthwaite A.B.,et al.Genomics 12:788-794(1992).
Nakamura Y.,et al.Exp. Hematol. 21:236-242(1993).
Freund D.,et al.Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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