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>   首页   >   产品   >   一抗   >   代谢   >   C1GALT1C1 Antibody (N-Term)   

C1GALT1C1 Antibody (N-Term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - C1GALT1C1 Antibody (N-Term) AP22217a
    All lanes : Anti-C1GALT1C1 Antibody (N-Term) at 1:2000 dilution Lane 1: Hela whole cell lysate Lane 2: HepG2 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 36 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession Q96EU7
Other Accession Q3SX46
Reactivity Human, Rat, Mouse
Predicted Bovine
Host Rabbit
Clonality polyclonal
Isotype Rabbit IgG
Calculated MW 36382 Da
Additional Information
Gene ID 29071
Other Names C1GALT1-specific chaperone 1, C38H2-like protein 1, C38H2-L1, Core 1 beta1, 3-galactosyltransferase 2, C1Gal-T2, C1GalT2, Core 1 beta3-Gal-T2, Core 1 beta3-galactosyltransferase-specific molecular chaperone, C1GALT1C1, COSMC
Target/Specificity This C1GALT1C1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 26-60 amino acids from human C1GALT1C1.
Dilution WB~~1:2000
E~~Use at an assay dependent concentration.
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsC1GALT1C1 Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name C1GALT1C1
Synonyms COSMC
Function Probable chaperone required for the generation of 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Probably acts as a specific molecular chaperone assisting the folding/stability of core 1 beta-3- galactosyltransferase (C1GALT1).
Cellular Location Membrane; Single-pass type II membrane protein
Tissue Location Ubiquitously expressed. Abundantly expressed in salivary gland, stomach, small intestine, kidney, and testis and at intermediate levels in whole brain, cerebellum, spinal cord, thymus, spleen, trachea, lung, pancreas, ovary, and uterus
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

Probable chaperone required for the generation of 1 O- glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Probably acts as a specific molecular chaperone assisting the folding/stability of core 1 beta-3-galactosyltransferase (C1GALT1).

REFERENCES

Kudo T.,et al.J. Biol. Chem. 277:47724-47731(2002).
Kudo T.,et al.J. Biol. Chem. 281:24999-24999(2006).
Ju T.,et al.Proc. Natl. Acad. Sci. U.S.A. 99:16613-16618(2002).
Rubboli F.,et al.Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases.
Zhang Q.-H.,et al.Genome Res. 10:1546-1560(2000).

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