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>   首页   >   产品   >   一抗   >   信号转导   >   RABEP2 Antibody   

RABEP2 Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - RABEP2 Antibody AP50625
    Western blot analysis of lysate from PC-3 cell line,using RABEP2 Antibody(AP50625). AP50625 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q9H5N1
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality polyclonal
Calculated MW 63543 Da
Additional Information
Gene ID 79874
Other Names Rab GTPase-binding effector protein 2, Rabaptin-5beta, RABEP2, RABPT5B
Dilution WB~~ 1:500
Format Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.09% (W/V) sodium azide and 50% glycerol.
Storage Conditions-20℃
Protein Information
Name RABEP2
Synonyms RABPT5B
Function Plays a role in membrane trafficking and in homotypic early endosome fusion (PubMed:9524116). Participates in arteriogenesis by regulating vascular endothelial growth factor receptor 2/VEGFR2 cell surface expression and endosomal trafficking (PubMed:29425100). By interacting with SDCCAG8, localizes to centrosomes and plays a critical role in ciliogenesis (PubMed:27224062).
Cellular Location Cytoplasm. Early endosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, cilium basal body
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

Plays a role in membrane trafficking and in homotypic early endosome fusion.

REFERENCES

Ota T.,et al.Nat. Genet. 36:40-45(2004).
Gournier H.,et al.EMBO J. 17:1930-1940(1998).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).
Van Damme P.,et al.Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012).

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