Anti-Melatonin Receptor 1a Antibody
Rabbit polyclonal antibody to Melatonin Receptor 1a
- 产品详情
- 实验流程
- 背景知识
Application ![]()
| WB |
---|---|
Primary Accession | P48039 |
Other Accession | Q61184 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 39375 Da |
Gene ID | 4543 |
---|---|
Other Names | Melatonin receptor type 1A; Mel-1A-R; Mel1a receptor |
Target/Specificity | Recognizes endogenous levels of Melatonin Receptor 1a protein. |
Dilution | WB~~WB (1/500 - 1/1000) |
Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | MTNR1A |
---|---|
Function | High affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity. Possibly involved in sleep induction, by melatonin activation of the potassium channel KCNMA1/BK and the dissociation of G-beta and G-gamma subunits, thereby decreasing synaptic transmission (By similarity). |
Cellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Location | Expressed in hypophyseal pars tuberalis and hypothalamic suprachiasmatic nuclei (SCN). Hippocampus |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Melatonin Receptor 1a. The exact sequence is proprietary.

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Cat# AP60190