Anti-Beta-actin Antibody-HRP labled
Rabbit polyclonal antibody to Beta-actin-HRP labled
- 产品详情
- 实验流程
- 背景知识
Application
| WB |
|---|---|
| Primary Accession | P60709 |
| Other Accession | P60710 |
| Reactivity | Human, Mouse, Rat, Rabbit, Monkey, Chicken, Drosophila |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 41737 Da |
| Gene ID | 60 |
|---|---|
| Other Names | Actin cytoplasmic 1; Beta-actin |
| Target/Specificity | KLH-conjugated synthetic peptide encompassing a sequence of human Beta-actin-HRP labled. The exact sequence is proprietary. |
| Dilution | WB~~WB (1/2000 - 1/5000) |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | ACTB |
|---|---|
| Function | Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells (PubMed:25255767, PubMed:29581253). Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction (PubMed:29581253). In addition to their role in the cytoplasmic cytoskeleton, G- and F- actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA (PubMed:29925947). Plays a role in the assembly of the gamma-tubulin ring complex (gTuRC), which regulates the minus-end nucleation of alpha-beta tubulin heterodimers that grow into microtubule protafilaments (PubMed:39321809, PubMed:38609661). Part of the ACTR1A/ACTB filament around which the dynactin complex is built (By similarity). The dynactin multiprotein complex activates the molecular motor dynein for ultra-processive transport along microtubules (By similarity). |
| Cellular Location | Cytoplasm, cytoskeleton. Nucleus Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
KLH-conjugated synthetic peptide encompassing a sequence of human Beta-actin-HRP labled. The exact sequence is proprietary.
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