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Caspase12 Polyclonal Antibody

     
  • 1 - Caspase12 Polyclonal Antibody AP68837
    Western Blot analysis of various cells using Caspase12 Polyclonal Antibody diluted at 1:500
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P
Primary Accession Q6UXS9
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 38907 Da
Additional Information
Gene ID 100506742
Other Names CASP12; Inactive caspase-12; CASP-12
Dilution WB~~Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
IHC-P~~N/A
Format Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide.
Storage Conditions-20℃
Protein Information
Name CASP12
Function May function as a negative regulator of inflammatory responses and innate immunity. May reduce cytokine release in response to bacterial lipopolysaccharide during infection. Reduces activation of NF-kappa-B in response to TNF (PubMed:15129283). May lack protease activity (Probable).
Tissue Location Widely expressed, with highest levels in lung.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

Has no protease activity. May reduce cytokine release in response to bacterial lipopolysaccharide during infections. Reduces activation of NF-kappa-B in response to TNF.

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